Hmmmmm, sounds like a strat will do the job you seek quite well. I'd consider the Fat Strat seeing as how Jimmy Page played a Les Paul with humbuckers, and about half of Zappas work was done on a Gibson SG with humbuckers as well.
Of course you could always go with a standard setup with three singles and use effects pedals to emulate the sound you are looking for. I use a Digitech RP200 A and there is no end to the sonic fury I can unleash.
